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Abstract

Introduction

         Wound Healing

         Chronic Ulcer Theory

         Current Treatments

         Fibronectin

         Hyaluronan

 

Product Design

       Product Design

 

Materials

       Materials

 

Methods

         Recombinant FN Fragment Purification

         Cell Culture

         Agarose Droplet Migration Assay

         Preparation of Hyaluronan Gel

         Hyaluronan Gel Three Dimensional Migration Assay

         Hyaluronan Gel Cell Toxicity Tests

 

Agarose-Droplet Migration Assay Validation

       Agarose-Droplet Migration Assay Validation

 

Agarose-Droplet Migration Assay Results

       Agarose-Droplet Migration Assay Results

 

Hyaluronan Migration Assay Validation

       Hyaluronan Migration Assay Validation

 

Hyaluronan Migration Assay Results

           Hyaluronan Migration Assay Results

 

Discussion and Conclusion

Discussion and Conclusion

 

Bibliography

           Bibliography

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